<p>You can use a simple javascript function. You need to refer to table to Javascript Key Codes for finding the code for each required key. The script function would be as follows:</p> <div style="line-height: normal"><span style="font-family: 'Courier New'; color: blue; font-size: 9pt">&lt;</span><span style="font-family: 'Courier New'; color: #a31515; font-size: 9pt">head</span><span style="font-family: 'Courier New'; font-size: 9pt"> <span style="color: red">runat</span><span style="color: blue">=&quot;server&quot;&gt;</span></span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp; <span style="color: blue">&lt;</span><span style="color: #a31515">title</span><span style="color: blue">&gt;&lt;/</span><span style="color: #a31515">title</span><span style="color: blue">&gt;</span></span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp; <span style="color: blue">&lt;</span><span style="color: #a31515">script</span> <span style="color: red">type</span><span style="color: blue">=&quot;text/javascript&quot;&gt;</span></span></div> <div style="line-height: normal">&nbsp;</div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <span style="color: blue">function</span> listenKeys(e) {</span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; e = e || window.event;</span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <span style="color: blue">var</span> code;</span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <span style="color: blue">if</span> (e.which)</span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; code = e.which;</span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <span style="color: blue">else</span></span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; code = e.keyCode;</span></div> <div style="line-height: normal">&nbsp;</div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <span style="color: green">// Write you conditions here</span></span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <span style="color: green">// You can check with or without modifiers - ctrlKey, shiftKey, altKey</span></span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <span style="color: green">// This is just an implementation of Ctrl+S</span></span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <span style="color: blue">if</span> (e.ctrlKey &amp;&amp; code == 83)</span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; document.getElementById(<span style="color: #a31515">'&lt;%=lbHome.ClientID %&gt;'</span>).click();</span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; }</span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; font-size: 9pt">&nbsp;&nbsp;&nbsp; <span style="color: blue">&lt;/</span><span style="color: #a31515">script</span><span style="color: blue">&gt;</span></span></div> <div style="line-height: normal"><span style="font-family: 'Courier New'; color: blue; font-size: 9pt">&lt;/</span><span style="font-family: 'Courier New'; color: #a31515; font-size: 9pt">head</span><span style="font-family: 'Courier New'; color: blue; font-size: 9pt">&gt;</span></div> <p>You can attach this function to the <strong>onload</strong> event of <strong>body</strong>.</p> <div style="margin: 0cm 0cm 10pt"><span style="line-height: 115%; font-family: 'Courier New'; color: blue; font-size: 9pt">&lt;</span><span style="line-height: 115%; font-family: 'Courier New'; color: #a31515; font-size: 9pt">body</span><span style="line-height: 115%; font-family: 'Courier New'; font-size: 9pt"> <span style="color: red">onkeydown</span><span style="color: blue">=&quot;listenKeys();&quot;&gt;</span></span></div>